RLA0 Polyclonal Antibody
Ucallm_WP0797-50
Price range: $268.00 through $328.00
Product details
Background:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which is the functional equivalent of the E. coli L10 ribosomal protein, belongs to the L10P family of ribosomal proteins. It is a neutral phosphoprotein with a C-terminal end that is nearly identical to the C-terminal ends of the acidic ribosomal phosphoproteins P1 and P2. The P0 protein can interact with P1 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. Transcript variants derived from alternative splicing exist; they encode the same protein. As is typical for genes encoding ribosomal pro
Specifications
| Size | 50μL/100μL |
| Target | RLA0 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 34kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 240-320 |
| Specificity | RLA0 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | RPLP0 |
| Protein Name | 60S acidic ribosomal protein P0 (60S ribosomal protein L10E) |
| Other Name | |
| Species | Human |
| Gene ID | 6175 |
| Uniprot | P05388, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P14869, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | P19945 |
| Cellular Localization | Nucleus . Cytoplasm . Localized in cytoplasmic mRNP granules containing untranslated mRNAs (PubMed:19188445, PubMed:17289661). . |
| Tissue Expression | Adipose tissue,Brain,Cervix,Cervix carcinoma,Colon,Coronary |
| Signaling_pathway | |
| Research Areas | >>Ribosome; / >>Coronavirus disease - COVID-19 |
| Function | Function:Ribosomal protein P0 is the functional equivalent of E.coli protein L10.,similarity:Belongs to the ribosomal protein L10P family.,subunit:P0 forms a pentameric complex by interaction with dimers of P1 and P2.,subunit:P0 forms a pentameric complex by interaction with dimers of P1 and P2. Interacts with Lassa virus Z protein., |
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