Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human RLBP1
Specificity
This antibody detects endogenous levels of RLBP1 at Human, Mouse
Gene Name
RLBP1 CRALBP
Protein Name
Retinaldehyde-binding protein 1 (Cellular retinaldehyde-binding protein)
Other Name
Species
Human
Gene ID
6017
Uniprot
P12271,
Species.1
Mouse
Gene ID.1
19771
Uniprot.1
Q9Z275
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Cytoplasm.
Tissue Expression
Retina and pineal gland. Not present in photoreceptor cells but is expressed abundantly in the adjacent retinal pigment epithelium (RPE) and in the Mueller glial cells of the retina.
Signaling_pathway
Research Areas
Function
Soluble retinoid carrier essential the proper function of both rod and cone photoreceptors. Participates in the regeneration of active 11-cis-retinol and 11-cis-retinaldehyde, from the inactive 11-trans products of the rhodopsin photocycle and in the de novo synthesis of these retinoids from 11-trans metabolic precursors. The cycling of retinoids between photoreceptor and adjacent pigment epithelium cells is known as the 'visual cycle'.