SKU: WP17295 Categories: ,

RLP24 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP17295-100
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Product details

Background:

This gene encodes a protein sharing a low level of sequence similarity with human ribosomal protein L24. Although this gene has been referred to as RPL24, L30, and 60S ribosomal protein L30 isolog in the sequence databases, it is distinct from the human genes officially named RPL24 (which itself has been referred to as ribosomal protein L30) and RPL30. The protein encoded by this gene localizes to the nucleolus and is thought to play a role in the biogenesis of the 60S ribosomal subunit. The precise function of this gene is currently unknown. This gene utilizes alternative polyadenylation signals and has multiple pseudogenes. [provided by RefSeq, Jul 2012],

Specifications

Size50μL/100μL
TargetRLP24
ReactivityHuman, Mouse, Rat
ApplicationsWB, IHC
MW(Calculated)18kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; IHC 1:50-300 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human RLP24 AA range: 91-141
SpecificityThis antibody detects endogenous levels of RLP24 at Human/Mouse/Rat
Gene NameRSL24D1 C15orf15 RPL24L My024
Protein NameRLP24
Other Name
SpeciesHuman
Gene ID51187
UniprotQ9UHA3,
Species.1Mouse
Gene ID.1225215
Uniprot.1Q99L28,
Species.2Rat
Gene ID.2363099
Uniprot.2Q6P6G7
Cellular LocalizationNucleus, nucleolus .
Tissue Expression
Signaling_pathway
Research Areas>>Ribosome; / >>Coronavirus disease - COVID-19
FunctionFunction:Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of GTPBP4/NOG1 to pre-60S particles.,similarity:Belongs to the ribosomal protein L24e family.,subunit:Associated with nucleolar and cytoplasmic pre-60S particles. At the end of biogenesis it dissociates from cytoplasmic pre-60S particles and is likely to be exchanged for its ribosomal homolog, RPL24.,
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