Price range: $268.00 through $328.00
Background:
This gene encodes an E3 ubiquitin ligase. The encoded protein plays a role in type 1 cytokine receptor signaling by controlling the balance between JAK2-associated cytokine receptor degradation and ectodomain shedding. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011],
| Size | 50μL/100μL |
| Target | RNF41 |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 34kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | RNF41 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | RNF41 FLRF NRDP1 SBBI03 |
| Protein Name | E3 ubiquitin-protein ligase NRDP1 (RING finger protein 41) |
| Other Name | |
| Species | Human |
| Gene ID | 10193 |
| Uniprot | Q9H4P4, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q8BH75 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | cytosol, |
| Tissue Expression | Detected in ovary, testis and prostate. |
| Signaling_pathway | |
| Research Areas | >>Endocytosis |
| Function | Function:Acts as E3 ubiquitin-protein ligase and regulates the degradation of target proteins, such as ERBB3.,pathway:Protein modification; protein ubiquitination.,PTM:Autoubiquitinated.,similarity:Contains 1 RING-type zinc finger.,similarity:Contains 1 SIAH-type zinc finger.,subunit:Interacts with USP8 and ERBB3.,tissue specificity:Detected in ovary, testis and prostate., |
