Price range: $268.00 through $328.00
Background:
This gene encodes a DNA-directed RNA polymerase I subunit. The encoded protein contains two potential zinc-binding motifs and may play a role in regulation of cell proliferation. The encoded protein may be involved in cancer and human immunodeficiency virus progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
| Size | 50μL/100μL |
| Target | RPA12 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 13kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | RPA12 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | ZNRD1 RPA12 |
| Protein Name | DNA-directed RNA polymerase I subunit RPA12 (Zinc ribbon domain-containing protein 1) |
| Other Name | |
| Species | Human |
| Gene ID | 30834 |
| Uniprot | Q9P1U0, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q791N7, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | Q6MFY5 |
| Cellular Localization | Nucleus, nucleolus . |
| Tissue Expression | Peripheral blood leukocyte,Skeletal muscle,Skin, |
| Signaling_pathway | |
| Research Areas | >>RNA polymerase |
| Function | Function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors.,similarity:Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.,similarity:Contains 1 TFIIS-type zinc finger.,subunit:Component of the RNA polymerase I (Pol I) complex consisting of at least 13 subunits., |
