RT31 Polyclonal Antibody
Ucallm_WP0772-50
Price range: $268.00 through $328.00
Product details
Background:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. The 28S subunit of the mammalian mitoribosome may play a crucial and characteristic role in translation initiation. This gene encodes a 28S subunit protein that has also been associated with type 1 diabetes; however, its relationship to the etiolog
Specifications
| Size | 50μL/100μL |
| Target | RT31 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 43kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 180-260 |
| Specificity | RT31 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | MRPS31 IMOGN38 |
| Protein Name | 28S ribosomal protein S31, mitochondrial (MRP-S31) (S31mt) (Imogen 38) |
| Other Name | |
| Species | Human |
| Gene ID | 10240 |
| Uniprot | Q92665, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q61733, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | B0BN56 |
| Cellular Localization | Mitochondrion . |
| Tissue Expression | Skin,Testis, |
| Signaling_pathway | |
| Research Areas | |
| Function | subunit:Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins., |
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