Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human RtcB
Specificity
This antibody detects endogenous levels of RtcB at Human, Mouse,Rat
Gene Name
C22orf28 HSPC117
Protein Name
tRNA-splicing ligase RtcB homolog (EC 6.5.1.3)
Other Name
Species
Human
Gene ID
51493
Uniprot
Q9Y3I0,
Species.1
Mouse
Gene ID.1
28088
Uniprot.1
Q99LF4,
Species.2
Rat
Gene ID.2
362855
Uniprot.2
Q6AYT3
Cellular Localization
Nucleus . Cytoplasm . Enters into the nucleus in case of active transcription while it accumulates in cytosol when transcription level is low. .
Tissue Expression
Signaling_pathway
Research Areas
Function
Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.