SKU: WP6369 Categories: ,

RtcB rabbit pAb

Price range: $268.00 through $328.00

SKU: WP6369-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetRTCB
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)56kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human RtcB
SpecificityThis antibody detects endogenous levels of RtcB at Human, Mouse,Rat
Gene NameC22orf28 HSPC117
Protein NametRNA-splicing ligase RtcB homolog (EC 6.5.1.3)
Other Name
SpeciesHuman
Gene ID51493
UniprotQ9Y3I0,
Species.1Mouse
Gene ID.128088
Uniprot.1Q99LF4,
Species.2Rat
Gene ID.2362855
Uniprot.2Q6AYT3
Cellular LocalizationNucleus . Cytoplasm . Enters into the nucleus in case of active transcription while it accumulates in cytosol when transcription level is low. .
Tissue Expression
Signaling_pathway
Research Areas
FunctionCatalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
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