Name: RXRγ Polyclonal Antibody
SKU: WP14385
Price: 268 USD
Availability: InStock

RXRγ Polyclonal Antibody

Ucallm_WP14385-50

Price range: $268.00 through $328.00

Size

100μl

50μl

Clear

SKU: WP14385-100

Enter the quantity you would like, or drag the panel to find the quantity and price that best for you

Bulk Quote Authorize OEM & ODM

Product details

Background:

retinoid X receptor gamma(RXRG) Homo sapiens This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2010],

Specifications

Size	50μL/100μL
Target	RXRγ
Reactivity	Human, Mouse
Applications	WB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)	50kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	The antiserum was produced against synthesized peptide derived from human Retinoid X Receptor gamma. AA range:171-220
Specificity	RXRγ Polyclonal Antibody detects endogenous levels of RXRγ protein.
Gene Name	RXRG
Protein Name	Retinoic acid receptor RXR-gamma
Other Name	RXRG; / NR2B3; / Retinoic acid receptor RXR-gamma; / Nuclear receptor subfamily 2 group B member 3; / Retinoid X receptor gamma
Species	Human
Gene ID	6258
Uniprot	P48443,
Species.1	Mouse
Gene ID.1	20183
Uniprot.1	P28705
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	Nucleus . Cytoplasm .
Tissue Expression	Expressed in aortic endothelial cells (at protein level).
Signaling_pathway	Organismal Systems >> Immune system >> Th17 cell differentiation;Organismal Systems >> Endocrine system >> Adipocytokine signaling pathway;Organismal Systems >> Endocrine system >> PPAR signaling pathway;Organismal Systems >> Endocrine system >> Thyroid hormone signaling pathway;Human Diseases >> Cancer: overview >> Pathways in cancer;Human Diseases >> Cancer: overview >> Transcriptional misregulation in cancer;Human Diseases >> Cancer: specific types >> Gastric cancer;Human Diseases >> Cancer: specific types >> Thyroid cancer;Human Diseases >> Cancer: specific types >> Small cell lung cancer;Human Diseases >> Cancer: specific types >> Non-small cell lung cancer
Research Areas	>>PPAR signaling pathway; / >>Th17 cell differentiation; / >>Thyroid hormone signaling pathway; / >>Adipocytokine signaling pathway; / >>Parathyroid hormone synthesis, secretion and action; / >>Pathways in cancer; / >>Transcriptional misregulation in cancer; / >>Chemical carcinogenesis - receptor activation; / >>Thyroid cancer; / >>Small cell lung cancer; / >>Non-small cell lung cancer; / >>Gastric cancer; / >>Lipid and atherosclerosis
Function	Caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,Domain:Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal steroid-binding domain.,Function:Nuclear hormone receptor. Involved in the retinoic acid response pathway. Binds 9-cis retinoic acid (9C-RA).,similarity:Belongs to the nuclear hormone receptor family. NR2 subfamily.,similarity:Contains 1 nuclear receptor DNA-binding domain.,