S-100A5 Polyclonal Antibody
Ucallm_WP14391-50
Price range: $268.00 through $328.00
Product details
Background:
S100 calcium binding protein A5(S100A5) Homo sapiens The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein has a Ca2+ affinity 20- to 100-fold higher than the other S100 proteins studied under identical conditions. This protein also binds Zn2+ and Cu2+, and Cu2+ strongly which impairs the binding of Ca2+. This protein is expressed in very restricted regions of the adult brain. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | S-100A5 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 32kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human S100A5. AA range:34-83 |
| Specificity | S-100A5 Polyclonal Antibody detects endogenous levels of S-100A5 protein. |
| Gene Name | S100A5 |
| Protein Name | Protein S100-A5 |
| Other Name | S100A5; / S100D; / Protein S100-A5; / Protein S-100D; / S100 calcium-binding protein A5 |
| Species | Human |
| Gene ID | 6276 |
| Uniprot | P33763, |
| Species.1 | Mouse |
| Gene ID.1 | 20199 |
| Uniprot.1 | P63084, |
| Species.2 | Rat |
| Gene ID.2 | 295211 |
| Uniprot.2 | P63083 |
| Cellular Localization | nucleus,neuronal cell body, |
| Tissue Expression | Brain,Kidney, |
| Signaling_pathway | |
| Research Areas | |
| Function | similarity:Belongs to the S-100 family.,similarity:Contains 2 EF-hand domains., |
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