SKU: WP1970 Categories: ,

S39A5 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP1970-100
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Product details

Background:

The protein encoded by this gene belongs to the ZIP family of zinc transporters that transport zinc into cells from outside, and play a crucial role in controlling intracellular zinc levels. Zinc is an essential cofactor for many enzymes and proteins involved in gene transcription, growth, development and differentiation. Mutations in this gene have been associated with autosomal dominant high myopia (MYP24). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014],

Specifications

Size50μL/100μL
TargetS39A5
ReactivityHuman, Mouse
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)59kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from part region of human protein
SpecificityS39A5 Polyclonal Antibody detects endogenous levels of protein.
Gene NameSLC39A5 ZIP5
Protein NameZinc transporter ZIP5 (Solute carrier family 39 member 5) (Zrt- and Irt-like protein 5) (ZIP-5)
Other Name
SpeciesHuman
Gene ID283375
UniprotQ6ZMH5,
Species.1Mouse
Gene ID.1
Uniprot.1Q9D856
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationBasolateral cell membrane; Multi-pass membrane protein .
Tissue ExpressionExpressed in liver, kidney, pancreas, small intestine, colon, spleen, fetal liver and fetal kidney.
Signaling_pathwayHuman Diseases >> Neurodegenerative disease >> Alzheimer disease;Human Diseases >> Neurodegenerative disease >> Parkinson disease
Research Areas>>Alzheimer disease; / >>Parkinson disease
FunctionFunction:May play a role in polarized cells by carrying out serosal-to-mucosal zinc transport. Seems to play a central role in controlling organismal zinc status.,PTM:Glycosylated.,similarity:Belongs to the ZIP transporter (TC 2.A.5) family.,tissue specificity:Expressed in liver, kidney, pancreas, small intestine, colon, spleen, fetal liver and fetal kidney.,
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