SKU: WP1746 Categories: ,

S6A18 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP1746-100
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Product details

Background:

The SLC6 family of proteins, which includes SLC6A18, act as specific transporters for neurotransmitters, amino acids, and osmolytes like betaine, taurine, and creatine. SLC6 proteins are sodium cotransporters that derive the energy for solute transport from the electrochemical gradient for sodium ions (Hoglund et al., 2005 [PubMed 16125675]).[supplied by OMIM, Apr 2010],

Specifications

Size50μL/100μL
TargetS6A18
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)69kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from part region of human protein
SpecificityS6A18 Polyclonal Antibody detects endogenous levels of protein.
Gene NameSLC6A18 XTRP2
Protein NameSodium-dependent neutral amino acid transporter B(0)AT3 (Sodium- and chloride-dependent transporter XTRP2) (Solute carrier family 6 member 18) (System B(0) neutral amino acid transporter AT3)
Other Name
SpeciesHuman
Gene ID348932
UniprotQ96N87,
Species.1Mouse
Gene ID.1
Uniprot.1O88576,
Species.2Rat
Gene ID.2
Uniprot.2Q62687
Cellular LocalizationMembrane; Multi-pass membrane protein .
Tissue ExpressionAbundantly expressed in kidney, but not in intestine.
Signaling_pathway
Research Areas
Functionsimilarity:Belongs to the sodium:neurotransmitter symporter (SNF) family.,tissue specificity:Abundantly expressed in kidney, but not in intestine.,
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