SKU: WM0414 Categories: ,

SAPAP1 Monoclonal Antibody

Price range: $268.00 through $328.00

SKU: WM0414-50
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Product details

Background:
function:Part of the postsynaptic scaffold in neuronal cells., similarity:Belongs to the SAPAP family., subcellular location:Found in postsynaptic density of neuronal cells., subunit:Interacts with guanylate kinase-like domain of DLG1, DLG2, DLG3, DLG4 and AIP1. Interacts with the PDZ domain of SHANK1, SHANK2 and SHANK3. Found in a complex with DLG4 and SHANK1, SHANK2 or SHANK3. Found in a complex with DLG4 and BEGAIN. Interacts with DYL2 and LRFN1., tissue specificity:Expressed in brain.,

Specifications

Size50μL/100μL
TargetSAPAP1
ReactivityHuman
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)109kD
MW(Observed)
Host SpeciesMouse
Isotype
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IHC 1:200-1:1000; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationAffinity purification
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
ClonalityMonoclonal
Clone Number1B9
ImmunogenPurified recombinant fragment of human SAPAP1 expressed in E. Coli.
SpecificitySAPAP1 Monoclonal Antibody detects endogenous levels of SAPAP1 protein.
Gene NameDLGAP1
Protein NameDisks large-associated protein 1
Other NameDLGAP1; / DAP1; / GKAP; / Disks large-associated protein 1; / DAP-1; / Guanylate kinase-associated protein; / hGKAP; / PSD-95/SAP90-binding protein 1; / SAP90/PSD-95-associated protein 1; / SAPAP1
SpeciesHuman
Gene ID9229
UniprotO14490,
Species.1Mouse
Gene ID.1
Uniprot.1Q9D415
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCell membrane; Peripheral membrane protein . Cell junction, synapse, postsynaptic density . Cell junction, synapse .
Tissue ExpressionExpressed in brain.
Signaling_pathwayOrganismal Systems >> Nervous system >> Glutamatergic synapse
Research Areas>>Glutamatergic synapse
FunctionFunction:Part of the postsynaptic scaffold in neuronal cells.,similarity:Belongs to the SAPAP family.,subcellular location:Found in postsynaptic density of neuronal cells.,subunit:Interacts with guanylate kinase-like domain of DLG1, DLG2, DLG3, DLG4 and AIP1. Interacts with the PDZ domain of SHANK1, SHANK2 and SHANK3. Found in a complex with DLG4 and SHANK1, SHANK2 or SHANK3. Found in a complex with DLG4 and BEGAIN. Interacts with DYL2 and LRFN1.,tissue specificity:Expressed in brain.,
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