SAPAP1 Monoclonal Antibody
Ucallm_WM0414-50
Price range: $268.00 through $328.00
Product details
Background:
function:Part of the postsynaptic scaffold in neuronal cells., similarity:Belongs to the SAPAP family., subcellular location:Found in postsynaptic density of neuronal cells., subunit:Interacts with guanylate kinase-like domain of DLG1, DLG2, DLG3, DLG4 and AIP1. Interacts with the PDZ domain of SHANK1, SHANK2 and SHANK3. Found in a complex with DLG4 and SHANK1, SHANK2 or SHANK3. Found in a complex with DLG4 and BEGAIN. Interacts with DYL2 and LRFN1., tissue specificity:Expressed in brain.,
Specifications
| Size | 50μL/100μL |
| Target | SAPAP1 |
| Reactivity | Human |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | 109kD |
| MW(Observed) | |
| Host Species | Mouse |
| Isotype | |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | Affinity purification |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | 1B9 |
| Immunogen | Purified recombinant fragment of human SAPAP1 expressed in E. Coli. |
| Specificity | SAPAP1 Monoclonal Antibody detects endogenous levels of SAPAP1 protein. |
| Gene Name | DLGAP1 |
| Protein Name | Disks large-associated protein 1 |
| Other Name | DLGAP1; / DAP1; / GKAP; / Disks large-associated protein 1; / DAP-1; / Guanylate kinase-associated protein; / hGKAP; / PSD-95/SAP90-binding protein 1; / SAP90/PSD-95-associated protein 1; / SAPAP1 |
| Species | Human |
| Gene ID | 9229 |
| Uniprot | O14490, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q9D415 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cell membrane; Peripheral membrane protein . Cell junction, synapse, postsynaptic density . Cell junction, synapse . |
| Tissue Expression | Expressed in brain. |
| Signaling_pathway | Organismal Systems >> Nervous system >> Glutamatergic synapse |
| Research Areas | >>Glutamatergic synapse |
| Function | Function:Part of the postsynaptic scaffold in neuronal cells.,similarity:Belongs to the SAPAP family.,subcellular location:Found in postsynaptic density of neuronal cells.,subunit:Interacts with guanylate kinase-like domain of DLG1, DLG2, DLG3, DLG4 and AIP1. Interacts with the PDZ domain of SHANK1, SHANK2 and SHANK3. Found in a complex with DLG4 and SHANK1, SHANK2 or SHANK3. Found in a complex with DLG4 and BEGAIN. Interacts with DYL2 and LRFN1.,tissue specificity:Expressed in brain., |
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