Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human SHLB1 AA range: 45-95
Sequence
Specificity
This antibody detects endogenous levels of human SHLB1
Gene Name
SH3GLB1 KIAA0491 CGI-61
Protein Name
Endophilin-B1 (Bax-interacting factor 1) (Bif-1) (SH3 domain-containing GRB2-like protein B1)
Other Name
Species
Human
Gene ID-1
51100
Uniprot
Q9Y371,
Species.1
Mouse
Gene ID-2
54673
Uniprot.1
Q9JK48,
Species.2
Rat
Gene ID-3
54673
Uniprot.2
Q6AYE2
Organism-4
Gene ID-4
SwissProt-4
Background
Cellular Localization
Cytoplasm . Golgi apparatus membrane; Peripheral membrane protein . Mitochondrion outer membrane; Peripheral membrane protein . Cytoplasmic vesicle, autophagosome membrane . Midbody . Association with the Golgi apparatus depends on the cell type (By similarity). Following starvation colocalizes with ATG5 and LC3 autophagy-related protein(s)on autophagosomal membranes (PubMed:17891140). .
Tissue Expression
Highly expressed in heart, skeletal muscle, kidney and placenta. Detected at lower levels in brain, colon, thymus, spleen, liver, small intestine, lung and peripheral blood leukocytes.
Signaling_pathway
Cellular Processes >> Transport and catabolism >> Autophagy - animal