SKU: WP5247 Categories: ,

SHLB1 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP5247-100
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Product details

Background:

Specifications

TargetSHLB1
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)40kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Modification
Recommended Dilution RatioWB 1:1000-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human SHLB1 AA range: 45-95
Sequence
SpecificityThis antibody detects endogenous levels of human SHLB1
Gene NameSH3GLB1 KIAA0491 CGI-61
Protein NameEndophilin-B1 (Bax-interacting factor 1) (Bif-1) (SH3 domain-containing GRB2-like protein B1)
Other Name
SpeciesHuman
Gene ID-151100
UniprotQ9Y371,
Species.1Mouse
Gene ID-254673
Uniprot.1Q9JK48,
Species.2Rat
Gene ID-354673
Uniprot.2Q6AYE2
Organism-4
Gene ID-4
SwissProt-4
Background
Cellular LocalizationCytoplasm . Golgi apparatus membrane; Peripheral membrane protein . Mitochondrion outer membrane; Peripheral membrane protein . Cytoplasmic vesicle, autophagosome membrane . Midbody . Association with the Golgi apparatus depends on the cell type (By similarity). Following starvation colocalizes with ATG5 and LC3 autophagy-related protein(s)on autophagosomal membranes (PubMed:17891140). .
Tissue ExpressionHighly expressed in heart, skeletal muscle, kidney and placenta. Detected at lower levels in brain, colon, thymus, spleen, liver, small intestine, lung and peripheral blood leukocytes.
Signaling_pathwayCellular Processes >> Transport and catabolism >> Autophagy - animal
Research Areas>>Autophagy - animal; / >>Endocytosis
Function
RRID
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