SKU: WP7863 Categories: ,

SHQ1 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP7863-100
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Product details

Background:

Specifications

TargetSHQ1
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)63kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Modification
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human SHQ1
Sequence
SpecificityThis antibody detects endogenous levels of SHQ1 at Human, Mouse
Gene NameSHQ1
Protein NameProtein SHQ1 homolog
Other Name
SpeciesHuman
Gene ID-155164
UniprotQ6PI26,
Species.1Mouse
Gene ID-272171
Uniprot.1Q7TMX5
Species.2
Gene ID-3
Uniprot.2
Organism-4
Gene ID-4
SwissProt-4
Background
Cellular LocalizationCytoplasm, cytosol . Nucleus, nucleoplasm . May at least partially shuttle between cytosol and nucleoplasm. In the nucleoplasm, exhibits a granular pattern, but is excluded from nucleoli and Cajal bodies. Absent from most H/ACA-box RNA transcription sites.
Tissue Expression
Signaling_pathway
Research Areas
FunctionRequired for the quantitative accumulation of H/ACA ribonucleoproteins (RNPs), including telomerase, probably through the stabilization of DKC1, from the time of its synthesis until its association with NOP10, NHP2, and NAF1 at the nascent H/ACA RNA.
RRID
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