Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human SHQ1
Sequence
Specificity
This antibody detects endogenous levels of SHQ1 at Human, Mouse
Gene Name
SHQ1
Protein Name
Protein SHQ1 homolog
Other Name
Species
Human
Gene ID-1
55164
Uniprot
Q6PI26,
Species.1
Mouse
Gene ID-2
72171
Uniprot.1
Q7TMX5
Species.2
Gene ID-3
Uniprot.2
Organism-4
Gene ID-4
SwissProt-4
Background
Cellular Localization
Cytoplasm, cytosol . Nucleus, nucleoplasm . May at least partially shuttle between cytosol and nucleoplasm. In the nucleoplasm, exhibits a granular pattern, but is excluded from nucleoli and Cajal bodies. Absent from most H/ACA-box RNA transcription sites.
Tissue Expression
Signaling_pathway
Research Areas
Function
Required for the quantitative accumulation of H/ACA ribonucleoproteins (RNPs), including telomerase, probably through the stabilization of DKC1, from the time of its synthesis until its association with NOP10, NHP2, and NAF1 at the nascent H/ACA RNA.