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Home/Reagents/Antibody/Primary antibody/Polyclonal Antibody/Rabbit pAb/SIA8B Polyclonal Antibody
SKU: WP3288 Categories: ,

SIA8B Polyclonal Antibody

Ucallm_WP3288-50

Price range: $268.00 through $328.00

SKU: WP3288-100
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Product details

Background:

The protein encoded by this gene is a type II membrane protein that is thought to catalyze the transfer of sialic acid from CMP-sialic acid to N-linked oligosaccharides and glycoproteins. The encoded protein may be found in the Golgi apparatus and may be involved in the production of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). This protein is a member of glycosyltransferase family 29. [provided by RefSeq, Jul 2008],

Specifications

TargetSIA8B
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)41kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Modification
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
Source
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from part region of human protein
Sequence
SpecificitySIA8B Polyclonal Antibody detects endogenous levels of protein.
Gene NameST8SIA2 SIAT8B STX
Protein NameAlpha-2,8-sialyltransferase 8B (Sialyltransferase 8B) (SIAT8-B) (Sialyltransferase X) (STX) (Sialytransferase St8Sia II) (ST8SiaII)
Other Name
SpeciesHuman
Gene ID-18128
UniprotQ92186,
Species.1Mouse
Gene ID-2
Uniprot.1O35696,
Species.2Rat
Gene ID-3
Uniprot.2Q07977
Organism-4
Gene ID-4
SwissProt-4
BackgroundThe protein encoded by this gene is a type II membrane protein that is thought to catalyze the transfer of sialic acid from CMP-sialic acid to N-linked oligosaccharides and glycoproteins. The encoded protein may be found in the Golgi apparatus and may be involved in the production of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). This protein is a member of glycosyltransferase family 29. [provided by RefSeq, Jul 2008],
Cellular LocalizationGolgi apparatus membrane; Single-pass type II membrane protein .
Tissue ExpressionHighly expressed in fetal brain, kidney and heart and to a much lesser extent in adult heart and thymus.
Signaling_pathway
Research Areas
FunctionFunction:May transfer sialic acid through alpha-2,8-linkages to the alpha-2,3-linked and alpha-2,6-linked sialic acid of N-linked oligosaccharides of glycoproteins and may be involved in PSA (polysialic acid) expression.,online information:GlycoGene database,online information:ST8Sia II,pathway:Protein modification; protein glycosylation.,similarity:Belongs to the glycosyltransferase 29 family.,tissue specificity:Highly expressed in fetal brain, kidney and heart and to a much lesser extent in adult heart and thymus.,
RRID
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