Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human SIPA1L1
Sequence
Specificity
This antibody detects endogenous levels of SIPA1L1 at Human, Mouse,Rat
Gene Name
SIPA1L1 E6TP1 KIAA0440
Protein Name
Signal-induced proliferation-associated 1-like protein 1 (SIPA1-like protein 1) (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6-targeted protein 1)
Other Name
Species
Human
Gene ID-1
26037
Uniprot
O43166,
Species.1
Mouse
Gene ID-2
217692
Uniprot.1
Q8C0T5,
Species.2
Rat
Gene ID-3
246212
Uniprot.2
O35412
Organism-4
Gene ID-4
SwissProt-4
Background
Cellular Localization
Cytoplasm, cytoskeleton . Cell junction, synapse, postsynaptic density . Cell junction, synapse, synaptosome . Associated with the actin cytoskeleton. Detected at synapses and dendritic spines of cultured hippocampal neurons (By similarity). .
Tissue Expression
Widely expressed.
Signaling_pathway
Environmental Information Processing >> Signal transduction >> Rap1 signaling pathway
Research Areas
Function
Stimulates the GTPase activity of RAP2A. Promotes reorganization of the actin cytoskeleton and recruits DLG4 to F-actin. Contributes to the regulation of dendritic spine morphogenesis (By similarity).