SNX4 Polyclonal Antibody
Product details
Background:
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associated with the long isoform of the leptin receptor and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor in cell cultures, but its function is unknown. This protein may form oligomeric complexes with family members. Two transcript variants, one protein coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Nov 2012],
Specifications
| Size | 50μL/100μL |
| Target | SNX4 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| MW(Calculated) | |
| MW(Observed) | 60kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; IHC 1:50-300 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SNX4. AA range:191-240 |
| Specificity | SNX4 Polyclonal Antibody detects endogenous levels of SNX4 protein. |
| Gene Name | SNX4 |
| Protein Name | Sorting nexin-4 |
| Other Name | SNX4; / Sorting nexin-4 |
| Species | Human |
| Gene ID | 8723 |
| Uniprot | O95219, |
| Species.1 | Mouse |
| Gene ID.1 | 69150 |
| Uniprot.1 | Q91YJ2 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Early endosome membrane; Peripheral membrane protein; Cytoplasmic side . Also detected on a juxtanuclear endocytic recycling compartment (ERC). . |
| Tissue Expression | Liver,Skin, |
| Signaling_pathway | |
| Research Areas | >>Endocytosis |
| Function | Function:May be involved in several stages of intracellular trafficking.,similarity:Belongs to the sorting nexin family.,similarity:Contains 1 PX (phox homology) domain., |
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