SOX7 Polyclonal Antibody
Ucallm_WP0573-50
Price range: $268.00 through $328.00
Product details
Background:
SRY-box 7(SOX7) Homo sapiens This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may play a role in tumorigenesis. A similar protein in mice is involved in the regulation of the wingless-type MMTV integration site family (Wnt) pathway. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | SOX7 |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 42kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | SOX7 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | SOX7 |
| Protein Name | Transcription factor SOX-7 |
| Other Name | |
| Species | Human |
| Gene ID | 83595 |
| Uniprot | Q9BT81, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P40646 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . Cytoplasm . |
| Tissue Expression | Widely expressed in adult and fetal tissues. Present both in mesenchymal and epithelial cells in some adult tissues, including colon. Tends to be down-regulated in prostate adenocarcinomas and colorectal tumors due to promoter hypermethylation. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Transcriptional repressor. Binds to the DNA sequence 5'-AACAAT-3'.,similarity:Contains 1 HMG box DNA-binding domain., |
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