SKU: WP8601 Categories: ,

SPESP1 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP8601-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetSPESP1
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)39kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human SPESP1
SpecificityThis antibody detects endogenous levels of SPESP1 at Human, Mouse,Rat
Gene NameSPESP1 UNQ732/PRO1418
Protein NameSperm equatorial segment protein 1 (ESP) (Equatorial segment protein) (SP-ESP) (Glycosylated 38 kDa sperm protein C-7/8)
Other Name
SpeciesHuman
Gene ID246777
UniprotQ6UW49,
Species.1Mouse
Gene ID.166712
Uniprot.1Q9D5A0,
Species.2Rat
Gene ID.2501010
Uniprot.2A0JPP4
Cellular LocalizationCytoplasmic vesicle, secretory vesicle, acrosome . Small proacrosomal granules (during the Golgi phase), enlarged acrosomal vesicles (during the cap phase), acrosome (during the elongating phase), equatorial segment of the acrosome (during the maturation phase) (PubMed:12773409). After acrosome reaction localizes to the equatorial segment region in both noncapacitated and capacitated, acrosome-reacted sperm (By similarity). .
Tissue ExpressionHighly expressed in testis, where it is localized in the acrosome of postmeiotic stages of spermiogenesis (round and elongating spermatids and in ejaculated spermatozoa) (at protein level). Poorly expressed in placenta and fetal lung.
Signaling_pathway
Research Areas
FunctionInvolved in fertilization ability of sperm.
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