SR-5A Polyclonal Antibody
Ucallm_WP14573-50
Price range: $268.00 through $328.00
Product details
Background:
The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. The gene described in this record is a member of 5-hydroxytryptamine (serotonin) receptor family and encodes a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G-proteins. This protein has been shown to function in part through the regulation of intracellular Ca2+ mobilization. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | SR-5A |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 36kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human HTR5A. AA range:15-64 |
| Specificity | SR-5A Polyclonal Antibody detects endogenous levels of SR-5A protein. |
| Gene Name | HTR5A |
| Protein Name | 5-hydroxytryptamine receptor 5A |
| Other Name | HTR5A; / 5-hydroxytryptamine receptor 5A; / 5-HT-5; / 5-HT-5A; / 5-HT5A; / Serotonin receptor 5A |
| Species | Human |
| Gene ID | 3361 |
| Uniprot | P47898, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P30966 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. |
| Tissue Expression | Brain,Cerebellum, |
| Signaling_pathway | Environmental Information Processing >> Signal transduction >> Calcium signaling pathway |
| Research Areas | >>Calcium signaling pathway; / >>Neuroactive ligand-receptor interaction; / >>Serotonergic synapse |
| Function | Function:This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins.,similarity:Belongs to the G-protein coupled receptor 1 family., |
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