Product details
Background:
This gene encodes a member of the arginine/serine-rich splicing factor family. The encoded protein likely functions in mRNA processing. [provided by RefSeq, Feb 2009],
SRp75 Polyclonal Antibody
Ucallm_WP14585-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | SRp75 |
| Reactivity | Human, Mouse |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 57kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SFRS4. AA range:111-160 |
| Specificity | SRp75 Polyclonal Antibody detects endogenous levels of SRp75 protein. |
| Gene Name | SRSF4 |
| Protein Name | Serine/arginine-rich splicing factor 4 |
| Other Name | SRSF4; / SFRS4; / SRP75; / Serine/arginine-rich splicing factor 4; / Pre-mRNA-splicing factor SRP75; / SRP001LB; / Splicing factor; / arginine/serine-rich 4 |
| Species | Human |
| Gene ID | 6429 |
| Uniprot | Q08170, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q8VE97 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus speckle . |
| Tissue Expression | Aorta endothelial cell,Cerebrum,Epithelium,Lymph, |
| Signaling_pathway | |
| Research Areas | >>Spliceosome; / >>Herpes simplex virus 1 infection |
| Function | Function:A probable role in alternative splice site selection during pre-mRNA splicing.,PTM:Extensively phosphorylated on serine residues in the RS domain.,similarity:Belongs to the splicing factor SR family.,similarity:Contains 2 RRM (RNA recognition motif) domains.,subunit:Found in a pre-mRNA splicing complex with SFRS4, SFRS5, SNRNP70, SNRPA1, SRRM1 and SRRM2. Interacts with PNN., |
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