ST18 Polyclonal Antibody
Product details
Background:
function:Repressor that binds to DNA sequences containing a bipartite element consisting of a direct repeat of the sequence 5′-AAAGTTT-3′ separated by 2-9 nucleotides. Represses basal transcription activity from target promoters (By similarity). Inhibits colony formation in cultured breast cancer cells., similarity:Contains 6 C2HC-type zinc fingers., tissue specificity:Detected at low levels in heart, liver, kidney, skeletal muscel, pancreas, testis, ovary and prostate. Detected at even lower levels in mammary epithelial cells and breast cancer cells.,
Specifications
| Size | 50μL/100μL |
| Target | ST18 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 115kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:40000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ZNF387. AA range:41-90 |
| Specificity | ST18 Polyclonal Antibody detects endogenous levels of ST18 protein. |
| Gene Name | ST18 |
| Protein Name | Suppression of tumorigenicity 18 protein |
| Other Name | ST18; / KIAA0535; / ZNF387; / Suppression of tumorigenicity 18 protein; / Zinc finger protein 387 |
| Species | Human |
| Gene ID | 9705 |
| Uniprot | O60284, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q80TY4 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . |
| Tissue Expression | Detected at low levels in heart, liver, kidney, skeletal muscle, pancreas, testis, ovary and prostate. Detected at even lower levels in mammary epithelial cells and breast cancer cells. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Repressor that binds to DNA sequences containing a bipartite element consisting of a direct repeat of the sequence 5'-AAAGTTT-3' separated by 2-9 nucleotides. Represses basal transcription activity from target promoters (By similarity). Inhibits colony formation in cultured breast cancer cells.,similarity:Contains 6 C2HC-type zinc fingers.,tissue specificity:Detected at low levels in heart, liver, kidney, skeletal muscel, pancreas, testis, ovary and prostate. Detected at even lower levels in mammary epithelial cells and breast cancer cells., |
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