Price range: $268.00 through $328.00
Background:
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. However, the total genomic length of this gene is greater than that of other SULT1 genes. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | ST1B1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 33kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ST1B1 AA range: 223-273 |
| Specificity | This antibody detects endogenous levels of ST1B1 at Human/Mouse/Rat |
| Gene Name | SULT1B1 ST1B2 SULT1B2 |
| Protein Name | ST1B1 |
| Other Name | |
| Species | Human |
| Gene ID | 27284 |
| Uniprot | O43704, |
| Species.1 | Mouse |
| Gene ID.1 | 56362 |
| Uniprot.1 | Q9QWG7, |
| Species.2 | Rat |
| Gene ID.2 | 64305 |
| Uniprot.2 | P52847 |
| Cellular Localization | Cytoplasm . |
| Tissue Expression | Highly expressed in the liver, peripheral blood leukocytes, colon (mucosal lining), small intestine (jejunum) and spleen. A lesser expression was observed in the lung, placenta and thymus. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Catalyzes the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates dopamine, small phenols such as 1-naphthol and p-nitrophenol and thyroid hormones, including 3,3'-diiodothyronine, triidothyronine, reverse triiodothyronine and thyroxine.,similarity:Belongs to the sulfotransferase 1 family.,subunit:Monomer.,tissue specificity:Highly expressed in the liver, peripheral blood leukocytes, colon (mucosal lining), small intestine (jejunum) and spleen. A lesser expression was observed in the lung, placenta and thymus., |
