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Home/Reagents/Antibody/Primary antibody/Polyclonal Antibody/Rabbit pAb/ST2A1 Polyclonal Antibody
SKU: WP16053 Categories: ,

ST2A1 Polyclonal Antibody

Ucallm_WP16053-50

Price range: $268.00 through $328.00

SKU: WP16053-100
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Product details

Background:

This gene encodes a member of the sulfotransferase family. Sulfotransferases aid in the metabolism of drugs and endogenous compounds by converting these substances into more hydrophilic water-soluble sulfate conjugates that can be easily excreted. This protein catalyzes the sulfation of steroids and bile acids in the liver and adrenal glands, and may have a role in the inherited adrenal androgen excess in women with polycystic ovary syndrome. [provided by RefSeq, Mar 2010],

Specifications

Size50μL/100μL
TargetST2A1
ReactivityHuman, Mouse, Rat
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)34kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human ST2A1
SpecificityThis antibody detects endogenous levels of human ST2A1
Gene NameSULT2A1 HST STD
Protein NameST2A1
Other NameBile salt sulfotransferase; / Dehydroepiandrosterone sulfotransferase; / DHEA-ST; / Hydroxysteroid Sulfotransferase; / HST; / ST2; / ST2A3; / Sulfotransferase 2A1; / ST2A1
SpeciesHuman
Gene ID6822
UniprotQ06520
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCytoplasm .
Tissue ExpressionLiver, adrenal and at lower level in the kidney. Is present in human fetus in higher level in the adrenal than the liver and the kidney.
Signaling_pathway
Research Areas>>Metabolism of xenobiotics by cytochrome P450; / >>Bile secretion; / >>Chemical carcinogenesis - DNA adducts
FunctionCatalytic activity:3'-phosphoadenylyl sulfate + glycolithocholate = adenosine 3',5'-bisphosphate + glycolithocholate 3-sulfate.,Catalytic activity:3'-phosphoadenylyl sulfate + taurolithocholate = adenosine 3',5'-bisphosphate + taurolithocholate sulfate.,Function:Catalyzes the sulfation of steroids and bile acids in the liver and adrenal glands.,miscellaneous:Estrogens present in maternal circulation is predominantly derived from fetal dehydroepiandosterone sulfate which is hydrolyzed and metabolized to estrogens in placenta.,PTM:The N-terminus is blocked.,similarity:Belongs to the sulfotransferase 1 family.,subunit:Homodimer.,tissue specificity:Liver, adrenal and at lower level in the kidney. Is present in human fetus in higher level in the adrenal than the liver and the kidney.,
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