Sur-8 rabbit pAb
Ucallm_WP6174-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | SHOC2 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 64kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human Sur-8 |
| Specificity | This antibody detects endogenous levels of Sur-8 at Human, Mouse,Rat |
| Gene Name | SHOC2 KIAA0862 |
| Protein Name | Leucine-rich repeat protein SHOC-2 (Protein soc-2 homolog) (Protein sur-8 homolog) |
| Other Name | |
| Species | Human |
| Gene ID | 8036 |
| Uniprot | Q9UQ13, |
| Species.1 | Mouse |
| Gene ID.1 | 56392 |
| Uniprot.1 | O88520, |
| Species.2 | Rat |
| Gene ID.2 | 309548 |
| Uniprot.2 | Q6AYI5 |
| Cellular Localization | Cytoplasm . Nucleus . Translocates from cytoplasm to nucleus upon growth factor stimulation. . |
| Tissue Expression | |
| Signaling_pathway | Environmental Information Processing >> Signal transduction >> Ras signaling pathway |
| Research Areas | |
| Function | Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes. |
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