Product details
Background:
SURF4 rabbit pAb
Ucallm_WP7525-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | SURF4 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 30kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human SURF4 |
| Specificity | This antibody detects endogenous levels of SURF4 at Human, Mouse |
| Gene Name | SURF4 SURF-4 |
| Protein Name | Surfeit locus protein 4 |
| Other Name | |
| Species | Human |
| Gene ID | 6836 |
| Uniprot | O15260, |
| Species.1 | Mouse |
| Gene ID.1 | 20932 |
| Uniprot.1 | Q64310 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Endoplasmic reticulum membrane; Multi-pass membrane protein . Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein . Golgi apparatus membrane; Multi-pass membrane protein . Cycles between the endoplasmic reticulum and the Golgi. . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Endoplasmic reticulum cargo receptor that mediates the export of lipoproteins by recruiting cargos into COPII vesicles to facilitate their secretion . Acts as a cargo receptor for lipoproteins bearing both APOB and APOA1, thereby regulating lipoprotein delivery and the maintenance of lipid homeostasis . Synergizes with the GTPase SAR1B to mediate transport of circulating lipoproteins . Promotes the secretion of PCSK9 . Also mediates the efficient secretion of erythropoietin (EPO) . May also play a role in the maintenance of the architecture of the endoplasmic reticulum-Golgi intermediate compartment and of the Golgi . |
Please login to post questions
Related products
