Price range: $268.00 through $328.00
Background:
This gene encodes a human homolog of Drosophila splicing regulatory protein. This gene autoregulates its expression by control of splicing of its first two introns. In addition, it also regulates the splicing of fibronectin and CD45 genes. Two transcript variants encoding different isoforms have been identified. [provided by RefSeq, May 2012],
| Size | 50μL/100μL |
| Target | SWAP |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| MW(Calculated) | |
| MW(Observed) | 105kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; IHC 1:50-300 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SFRS8. AA range:201-250 |
| Specificity | SWAP Polyclonal Antibody detects endogenous levels of SWAP protein. |
| Gene Name | SFSWAP |
| Protein Name | Splicing factor suppressor of white-apricot homolog |
| Other Name | SFSWAP; / SFRS8; / SWAP; / Splicing factor; / suppressor of white-apricot homolog; / Splicing factor, arginine/serine-rich 8; / Suppressor of white apricot protein homolog |
| Species | Human |
| Gene ID | 6433 |
| Uniprot | Q12872, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q3USH5 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . |
| Tissue Expression | Brain,Epithelium,Eye,Placenta,Skin, |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:May function as an alternative splicing regulator. Regulate its own expression at the level of RNA processing. Also regulates the splicing of fibronectin and CD45 genes. May act, at least in part, by interaction with other R/S-containing splicing factors.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 2 SURP motif repeats., |
