Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human Synaptopodin
Specificity
This antibody detects endogenous levels of Synaptopodin at Human,Rat
Gene Name
SYNPO KIAA1029
Protein Name
Synaptopodin
Other Name
Species
Human
Gene ID
11346
Uniprot
Q8N3V7,
Species.1
Mouse
Gene ID.1
Uniprot.1
Q8CC35,
Species.2
Rat
Gene ID.2
60324
Uniprot.2
Q9Z327
Cellular Localization
Cytoplasm, cytoskeleton . Cell junction, tight junction . Perikaryon . Cell projection, dendritic spine . Cell junction, synapse, postsynaptic density . Cell junction, synapse . Cytoplasm, cytosol . Localized at the tight junction of cells. In brain, localized to the postsynaptic densities and in the perikarya. Associated with dendritic spines of a subset of synapses. .
Tissue Expression
Expressed in cerebral cortex.
Signaling_pathway
Cellular Processes >> Cellular community - eukaryotes >> Tight junction
Research Areas
Function
Actin-associated protein that may play a role in modulating actin-based shape and motility of dendritic spines and renal podocyte foot processes. Seems to be essential for the formation of spine apparatuses in spines of telencephalic neurons, which is involved in synaptic plasticity (By similarity).