Product details
Background:
SYNJ1 rabbit pAb
Ucallm_WP6818-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | SYNJ1 |
| Reactivity | Human, Rat |
| Applications | WB |
| MW(Calculated) | 173kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human SYNJ1 |
| Specificity | This antibody detects endogenous levels of SYNJ1 at Human,Rat |
| Gene Name | SYNJ1 KIAA0910 |
| Protein Name | Synaptojanin-1 (Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1) |
| Other Name | |
| Species | Human |
| Gene ID | 8867 |
| Uniprot | O43426, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q8CHC4, |
| Species.2 | Rat |
| Gene ID.2 | 85238 |
| Uniprot.2 | Q62910 |
| Cellular Localization | Cytoplasm, perinuclear region . |
| Tissue Expression | Concentrated at clathrin-coated endocytic intermediates in nerve terminals. Isoform 1 is more enriched than isoform 2 in developing brain as well as non-neuronal cells. Isoform 2 is very abundant in nerve terminals. |
| Signaling_pathway | |
| Research Areas | |
| Function | Phosphatase that acts on various phosphoinositides, including phosphatidylinositol 4-phosphate, phosphatidylinositol (4,5)-bisphosphate and phosphatidylinositol (3,4,5)-trisphosphate . Has a role in clathrin-mediated endocytosis (By similarity). Hydrolyzes PIP2 bound to actin regulatory proteins resulting in the rearrangement of actin filaments downstream of tyrosine kinase and ASH/GRB2 (By similarity). |
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