SYT3 Polyclonal Antibody
Product details
Background:
cofactor:Binds 3 calcium ions per subunit. The ions are bound to the C2 domains., domain:The first C2 domain mediates Ca(2+)-dependent phospholipid binding., function:May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis., similarity:Belongs to the synaptotagmin family., similarity:Contains 2 C2 domains., subunit:Homodimer. Can also form heterodimers.,
Specifications
| Size | 50μL/100μL |
| Target | SYT3 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 64kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | SYT3 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | SYT3 |
| Protein Name | Synaptotagmin-3 (Synaptotagmin III) (SytIII) |
| Other Name | |
| Species | Human |
| Gene ID | 84258 |
| Uniprot | Q9BQG1, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | O35681, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | P40748 |
| Cellular Localization | Cell membrane; Single-pass membrane protein . Cytoplasmic vesicle, secretory vesicle membrane; Single-pass membrane protein . |
| Tissue Expression | Expressed in melanocytes (PubMed:23999003). |
| Signaling_pathway | |
| Research Areas | |
| Function | cofactor:Binds 3 calcium ions per subunit. The ions are bound to the C2 domains.,Domain:The first C2 domain mediates Ca(2+)-dependent phospholipid binding.,Function:May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.,similarity:Belongs to the synaptotagmin family.,similarity:Contains 2 C2 domains.,subunit:Homodimer. Can also form heterodimers., |
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