T1R3 Polyclonal Antibody
Ucallm_WP14647-50
Price range: $268.00 through $328.00
Product details
Background:
The protein encoded by this gene is a G-protein coupled receptor involved in taste responses. The encoded protein can form a heterodimeric receptor with TAS1R1 to elicit the umami taste response, or it can bind with TAS1R2 to form a receptor for the sweet taste response. [provided by RefSeq, Nov 2015],
Specifications
| Size | 50μL/100μL |
| Target | T1R3 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 93kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TAS1R3. AA range:326-375 |
| Specificity | T1R3 Polyclonal Antibody detects endogenous levels of T1R3 protein. |
| Gene Name | TAS1R3 |
| Protein Name | Taste receptor type 1 member 3 |
| Other Name | TAS1R3; / T1R3; / TR3; / Taste receptor type 1 member 3; / Sweet taste receptor T1R3 |
| Species | Human |
| Gene ID | 83756 |
| Uniprot | Q7RTX0, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q925D8 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | >>Taste transduction; / >>Carbohydrate digestion and absorption |
| Function | Function:Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose (By similarity). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses.,online information:The taste experience -Issue 55 of February 2005,similarity:Belongs to the G-protein coupled receptor 3 family. TAS1R subfamily.,subunit:Forms homodimers or heterodimers with TAS1R1 and TAS1R2., |
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