SKU: WP14659 Categories: ,

T2R5 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP14659-100
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Product details

Background:

This gene encodes a bitter taste receptor; bitter taste receptors are members of the G protein-coupled receptor superfamily and are specifically expressed by taste receptor cells of the tongue and palate epithelia. Each of these apparently intronless taste receptor genes encodes a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes on chromosome 7 and is genetically linked to loci that influence bitter perception. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetT2R5
ReactivityHuman
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)35kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; ELISA 1:5000; Not yet tested in other applications.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human TAS2R5. AA range:178-227
SpecificityT2R5 Polyclonal Antibody detects endogenous levels of T2R5 protein.
Gene NameTAS2R5
Protein NameTaste receptor type 2 member 5
Other NameTAS2R5; / Taste receptor type 2 member 5; / T2R5
SpeciesHuman
Gene ID54429
UniprotQ9NYW4
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationMembrane; Multi-pass membrane protein.
Tissue ExpressionExpressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells.
Signaling_pathway
Research Areas>>Taste transduction
FunctionFunction:Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.,miscellaneous:Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli.,similarity:Belongs to the G-protein coupled receptor T2R family.,tissue specificity:Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells.,
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