Price range: $268.00 through $328.00
Background:
The protein encoded by this gene is a dehydratase that converts trans-3-hydroxy-L-proline to delta(1)-pyrroline-2-carboxylate. This enzyme may function to degrade dietary proteins that contain trans-3-hydroxy-L-proline as well as other proteins such as collagen IV. The encoded protein can be converted to an epimerase by changing a threonine to a cysteine at a catalytic site. [provided by RefSeq, Sep 2016],
| Size | 50μL/100μL |
| Target | T3HPD |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | |
| MW(Observed) | 38kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human T3HPD AA range: 11-61 |
| Specificity | This antibody detects endogenous levels of T3HPD at Human/Mouse |
| Gene Name | L3HYPDH C14orf149 |
| Protein Name | T3HPD |
| Other Name | Trans-L-3-hydroxyproline dehydratase; / Trans-3-hydroxy-l-proline dehydratase |
| Species | Human |
| Gene ID | 112849 |
| Uniprot | Q96EM0, |
| Species.1 | Mouse |
| Gene ID.1 | 67217 |
| Uniprot.1 | Q9CXA2 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | |
| Tissue Expression | Ubiquitously expressed. |
| Signaling_pathway | |
| Research Areas | >>Arginine and proline metabolism; / >>Metabolic pathways |
| Function | Catalytic activity:L-proline = D-proline.,Function:Catalyzes the interconversion of L- and D-proline.,miscellaneous:In contrast to the T.cruzi enzyme, lacks the conserved Cys at position 273 which is replaced by a Thr residue. The high conservation of the protein nevertheless suggests that it is nevertheless active.,similarity:Belongs to the proline racemase family.,subunit:Homodimer., |
