TBR1 [PTR1395] mouse mAb
Ucallm_WM1268-50
Price range: $268.00 through $328.00
Product details
Background:
This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of numerous developmental processes. In mouse, the ortholog of this gene is expressed in the cerebral cortex, hippocampus, amygdala and olfactory bulb and is thought to play an important role in neuronal migration and axonal projection. In mouse, the C-terminal region of this protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase. [provided by RefSeq, Dec 2015],
Specifications
| Size | 50μL/100μL |
| Target | TBR1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | 74kD |
| MW(Observed) | 74kD |
| Host Species | Mouse |
| Isotype | IgM,kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:100-400; WB 1:500-2000; IF 1:100-500; ELISA 1:1000-5000; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RMMR1395 |
| Immunogen | AA range: 1-682 |
| Specificity | This antibody detects endogenous levels of TBR1 protein. |
| Gene Name | TBR1 |
| Protein Name | T-box brain protein 1 (T-brain-1) (TBR-1) (TES-56) |
| Other Name | |
| Species | Human |
| Gene ID | 10716 |
| Uniprot | Q16650, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q64336 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus |
| Tissue Expression | Brain. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Probable transcriptional regulator involved in developmental processes. TBR1 is required for normal brain development.,similarity:Contains 1 T-box DNA-binding domain.,tissue specificity:Brain., |
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