TBX22 Polyclonal Antibody
Ucallm_WP14700-50
Price range: $268.00 through $328.00
Product details
Background:
T-box 22(TBX22) Homo sapiens This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene have been associated with the inherited X-linked disorder, Cleft palate with ankyloglossia, and it is believed to play a major role in human palatogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | TBX22 |
| Reactivity | Human, Mouse |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 58kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TBX22. AA range:1-50 |
| Specificity | TBX22 Polyclonal Antibody detects endogenous levels of TBX22 protein. |
| Gene Name | TBX22 |
| Protein Name | T-box transcription factor TBX22 |
| Other Name | TBX22; / TBOX22; / T-box transcription factor TBX22; / T-box protein 22 |
| Species | Human |
| Gene ID | 50945 |
| Uniprot | Q9Y458, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q8K402 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . |
| Tissue Expression | Seems to be expressed at a low level. |
| Signaling_pathway | |
| Research Areas | |
| Function | Disease:Defects in TBX22 are the cause of X-linked cleft palate with ankyloglossia (CPX) [MIM:303400].,Function:Probable transcriptional regulator involved in developmental processes. This is major determinant crucial to palatogenesis.,similarity:Contains 1 T-box DNA-binding domain.,tissue specificity:Seems to be expressed at a low level., |
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