TCP-1 β Monoclonal Antibody
Ucallm_WM0439-50
Price range: $268.00 through $328.00
Product details
Background:
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010],
Specifications
| Size | 50μL/100μL |
| Target | TCP-1 β |
| Reactivity | Human, Mouse, Rat, Monkey |
| Applications | WB, IF, FC, ELISA |
| MW(Calculated) | 57kD |
| MW(Observed) | |
| Host Species | Mouse |
| Isotype | |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IF 1:200-1:1000; Flow Cyt 1:200-1:400; ELISA 1:10000; Not yet tested in other applications. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | Affinity purification |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | 5H1 |
| Immunogen | Purified recombinant fragment of human TCP-1 β expressed in E. Coli. |
| Specificity | TCP-1 β Monoclonal Antibody detects endogenous levels of TCP-1 β protein. |
| Gene Name | CCT2 |
| Protein Name | T-complex protein 1 subunit beta |
| Other Name | CCT2; / 99D8.1; / CCTB; / T-complex protein 1 subunit beta; / TCP-1-beta; / CCT-beta |
| Species | Human |
| Gene ID | 10576 |
| Uniprot | P78371, |
| Species.1 | Mouse |
| Gene ID.1 | 12461 |
| Uniprot.1 | P80314, |
| Species.2 | Rat |
| Gene ID.2 | 299809 |
| Uniprot.2 | Q5XIM9 |
| Cellular Localization | Cytoplasm . |
| Tissue Expression | B-cell lymphoma,Brain,Cajal-Retzius cell,Fetal brain cortex,Liver,P |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Molecular chaperone; assist the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.,similarity:Belongs to the TCP-1 chaperonin family.,subunit:Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter. Interacts with PACRG., |
Please login to post questions
Related products
