TCPR2 rabbit pAb
Ucallm_WP17423-50
Price range: $268.00 through $328.00
Product details
Background:
The protein encoded by this gene is a member of the tectonin beta-propeller repeat-containing (TECPR) family, and contains both TECPR and tryptophan-aspartic acid repeat (WD repeat) domains. This gene has been implicated in autophagy, as reduced expression levels of this gene have been associated with impaired autophagy. Recessive mutations in this gene have been associated with a hereditary form of spastic paraparesis (HSP). HSP is characterized by progressive spasticity and paralysis of the legs. There is also some evidence linking mutations in this gene with birdshot chorioretinopathy (BSCR), which results in inflammation of the choroid and retina. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015],
Specifications
| Size | 50μL/100μL |
| Target | TCPR2 |
| Reactivity | Human |
| Applications | WB |
| MW(Calculated) | 155kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human TCPR2 AA range: 598-648 |
| Specificity | This antibody detects endogenous levels of TCPR2 at Human |
| Gene Name | TECPR2 KIAA0297 KIAA0329 |
| Protein Name | TCPR2 |
| Other Name | |
| Species | Human |
| Gene ID | 9895 |
| Uniprot | O15040 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | |
| Tissue Expression | Detected in skin fibroblast (at protein level). |
| Signaling_pathway | |
| Research Areas | |
| Function |
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