TDGF1 Polyclonal Antibody
Ucallm_WP2827-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. Pseudogenes of this gene are found on chromosomes 2, 3, 6, 8, 19 and X. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010],
Specifications
| Size | 50μL/100μL |
| Target | Cripto |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 20kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 21-70 |
| Specificity | TDGF1 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | TDGF1 CRIPTO |
| Protein Name | Teratocarcinoma-derived growth factor 1 (Cripto-1 growth factor) (CRGF) (Epidermal growth factor-like cripto protein CR1) |
| Other Name | |
| Species | Human |
| Gene ID | 6997 |
| Uniprot | P13385, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P51865 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cell membrane; Lipid-anchor, GPI-anchor . Secreted . Released from the cell membrane by GPI cleavage. . |
| Tissue Expression | Preferentially expressed in gastric and colorectal carcinomas than in their normal counterparts. Expressed in breast and lung. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm.,similarity:Contains 1 EGF-like domain.,tissue specificity:Preferentially expressed in gastric and colorectal carcinomas than in their normal counterparts., |
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