Price range: $268.00 through $328.00
Background:
This gene encodes a member of the TFB4 family. The encoded protein is a subunit of the core-TFIIH basal transcription factor and localizes to the nucleus. The encoded protein is involved in RNA transcription by RNA polymerase II and nucleotide excision repair and associates with the Cdk-activating kinase complex. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 14. [provided by RefSeq, Dec 2012],
| Size | 50μL/100μL |
| Target | TF2H3 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 34kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human TF2H3 AA range: 39-89 |
| Specificity | This antibody detects endogenous levels of TF2H3 at Human/Mouse/Rat |
| Gene Name | GTF2H3 |
| Protein Name | TF2H3 |
| Other Name | |
| Species | Human |
| Gene ID | 2967 |
| Uniprot | Q13889, |
| Species.1 | Mouse |
| Gene ID.1 | 209357 |
| Uniprot.1 | Q8VD76, |
| Species.2 | Rat |
| Gene ID.2 | 288651 |
| Uniprot.2 | Q561R7 |
| Cellular Localization | Nucleus . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | >>Basal transcription factors; / >>Nucleotide excision repair; / >>Viral carcinogenesis |
| Function | Function:Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Anchors XPB.,similarity:Belongs to the TFB4 family.,subunit:One of the six subunits forming the core-TFIIH basal transcription factor., |
