Product details
Background:
TFAP2E rabbit pAb
Ucallm_WP8485-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | TFAP2E |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 49kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human TFAP2E |
| Specificity | This antibody detects endogenous levels of TFAP2E at Human, Mouse |
| Gene Name | TFAP2E |
| Protein Name | Transcription factor AP-2-epsilon (AP2-epsilon) (Activating enhancer-binding protein 2-epsilon) |
| Other Name | |
| Species | Human |
| Gene ID | 339488 |
| Uniprot | Q6VUC0, |
| Species.1 | Mouse |
| Gene ID.1 | 332937 |
| Uniprot.1 | Q6VUP9 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . |
| Tissue Expression | Expressed in skin, primary keratinocytes, immortalized keratinocytes, and HeLa cell line. |
| Signaling_pathway | |
| Research Areas | |
| Function | Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-epsilon may play a role in the development of the CNS and in cartilage differentiation (By similarity). |
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