TG1019 Polyclonal Antibody
Product details
Background:
function:Receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E, 8Z, 11Z, 14Z-eicosatetraenoic acid (5-OXO-ETE), 5(S)-hydroperoxy-6E, 8Z, 11Z, 14Z-eicosatetraenoic acid (5(S)-HPETE) and arachidonic acid. Seems to be coupled to the G(i)/G(o), families of heteromeric G proteins., similarity:Belongs to the G-protein coupled receptor 1 family., tissue specificity:Expressed in various tissues except brain. Expression is more intense in liver, kidney, peripheral leukocyte, lung, and spleen than in other tissues. Highly expressed in eosinophils, neutrophils, and lung macrophages.,
Specifications
| Size | 50μL/100μL |
| Target | TG1019 |
| Reactivity | Human |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 46kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human OXER1. AA range:212-261 |
| Specificity | TG1019 Polyclonal Antibody detects endogenous levels of TG1019 protein. |
| Gene Name | OXER1 |
| Protein Name | Oxoeicosanoid receptor 1 |
| Other Name | OXER1; / GPR170; / TG1019; / Oxoeicosanoid receptor 1; / 5-oxo-ETE G-protein coupled receptor; / G-protein coupled receptor 170; / G-protein coupled receptor R527; / G-protein coupled receptor TG1019 |
| Species | Human |
| Gene ID | 165140 |
| Uniprot | Q8TDS5 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. |
| Tissue Expression | Expressed in various tissues except brain. Expression is more intense in liver, kidney, peripheral leukocyte, lung, and spleen than in other tissues. Highly expressed in eosinophils, neutrophils, and lung macrophages. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OXO-ETE), 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid (5(S)-HPETE) and arachidonic acid. Seems to be coupled to the G(i)/G(o), families of heteromeric G proteins.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in various tissues except brain. Expression is more intense in liver, kidney, peripheral leukocyte, lung, and spleen than in other tissues. Highly expressed in eosinophils, neutrophils, and lung macrophages., |
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