Name: TGFβ RIII (phospho Thr842) Polyclonal Antibody
SKU: WP10190
Price: 288 USD
Availability: InStock

TGFβ RIII (phospho Thr842) Polyclonal Antibody

Ucallm_WP10190-50

Price range: $288.00 through $368.00

Size

100μl

50μl

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SKU: WP10190-100

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Product details

Background:

This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010],

Specifications

Target	TGFβ RIII
Reactivity	Human, Mouse, Rat
Applications	IHC, IF, ELISA
MW(Calculated)	93kD
MW(Observed)
Host Species	Rabbit
Isotype	IgG
Conjugate
Modification	Phospho
Recommended Dilution Ratio	IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.
Composition	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Purification Process	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage Condition	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	The antiserum was produced against synthesized peptide derived from human TGF beta Receptor III around the phosphorylation site of Thr842. AA range:801-850
Sequence
Specificity	Phospho-TGFβ RIII (T842) Polyclonal Antibody detects endogenous levels of TGFβ RIII protein only when phosphorylated at T842.
Gene Name	TGFBR3
Protein Name	Transforming growth factor beta receptor type 3
Alias	TGFBR3;Transforming growth factor beta receptor type 3;TGF-beta receptor type 3;TGFR-3;Betaglycan;Transforming growth factor beta receptor III;TGF-beta receptor type III
Organism-1	Human
Gene ID-1	7049
SwissProt-1	Q03167
Organism-2	Mouse
Gene ID-2	21814
SwissProt-2	O88393
Organism-3	Rat
Gene ID-3	29610
SwissProt-3	P26342
Organism-4
Gene ID-4
SwissProt-4
Cellular Localization	Secreted. Secreted, extracellular space. Cell membrane ; Single-pass type I membrane protein . Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix.