Price range: $268.00 through $328.00
Background:
The encoded protein catalyzes the last step of the mitochondrial fatty acid beta-oxidation spiral. Unlike most mitochondrial matrix proteins, it contains a non-cleavable amino-terminal targeting signal. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | THIM |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 43kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 110-190 |
| Specificity | THIM Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | ACAA2 |
| Protein Name | 3-ketoacyl-CoA thiolase, mitochondrial (Acetyl-CoA acyltransferase) (Beta-ketothiolase) (Mitochondrial 3-oxoacyl-CoA thiolase) (T1) |
| Other Name | |
| Species | Human |
| Gene ID | 10449 |
| Uniprot | P42765, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q8BWT1, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | P13437 |
| Cellular Localization | Mitochondrion . |
| Tissue Expression | Adipocyte,Liver,Lung, |
| Signaling_pathway | |
| Research Areas | >>Fatty acid elongation; / >>Fatty acid degradation; / >>Valine, leucine and isoleucine degradation; / >>Metabolic pathways; / >>Fatty acid metabolism |
| Function | Catalytic activity:Acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA.,pathway:Lipid metabolism; fatty acid metabolism.,similarity:Belongs to the thiolase family.,subunit:Homotetramer., |
