Price range: $268.00 through $328.00
Background:
This gene encodes a multi-pass transmembrane protein. Reduced expression of this gene in mouse fibroblasts causes short cilia and failure of ciliogenesis. Expression of this gene is tightly coordinated with expression of the neighboring gene TMEM216. Mutations in this gene are associated with the autosomal recessive neurodevelopmental disorder Joubert Syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012],
| Size | 50μL/100μL |
| Target | TM138 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 18kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human TM138 AA range: 75-125 |
| Specificity | This antibody detects endogenous levels of TM138 at Human/Mouse/Rat |
| Gene Name | TMEM138 HSPC196 HSPC198 |
| Protein Name | TM138 |
| Other Name | |
| Species | Human |
| Gene ID | 51524 |
| Uniprot | Q9NPI0, |
| Species.1 | Mouse |
| Gene ID.1 | 72982 |
| Uniprot.1 | Q9D6G5, |
| Species.2 | Rat |
| Gene ID.2 | 361728 |
| Uniprot.2 | B1WBM3 |
| Cellular Localization | Vacuole membrane; Multi-pass membrane protein . Cell projection, cilium . Localizes to vesicles en route to the base of cilium. |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | similarity:Belongs to the TMEM138 family., |
