Product details
Background:
TMEM55A catalyzes the degradation of phosphatidylinositol 4, 5-bisphosphate (PtdIns-4, 5-P2) by removing the 4-phosphate (Ungewickell et al., 2005 [PubMed 16365287]).[supplied by OMIM, Mar 2008],
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TM55A rabbit pAb
Ucallm_WP17242-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | TM55A |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 28kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human TM55A AA range: 33-83 |
| Specificity | This antibody detects endogenous levels of TM55A at Human/Mouse/Rat |
| Gene Name | TMEM55A |
| Protein Name | TM55A |
| Other Name | |
| Species | Human |
| Gene ID | 55529 |
| Uniprot | Q8N4L2, |
| Species.1 | Mouse |
| Gene ID.1 | 72519 |
| Uniprot.1 | Q9CZX7, |
| Species.2 | Rat |
| Gene ID.2 | 362490 |
| Uniprot.2 | Q4V888 |
| Cellular Localization | Late endosome membrane; Multi-pass membrane protein . Lysosome membrane; Multi-pass membrane protein . Cytoplasmic vesicle, phagosome membrane; Multi-pass membrane protein . Cell membrane; Multi-pass membrane protein . |
| Tissue Expression | Ubiquitous. |
| Signaling_pathway | |
| Research Areas | >>Phosphatidylinositol signaling system |
| Function | Catalytic activity:1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 5-phosphate + phosphate.,Catalytic activity:1-phosphatidyl-myo-inositol 4,5-bisphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 5-phosphate + phosphate.,Function:Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 4,5-bisphosphate. Does not hydrolyze phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-bisphosphate, inositol 3,5-bisphosphate, inositol 3,4-bisphosphate, phosphatidylinositol 5-monophosphate, phosphatidylinositol 4-monophosphate and phosphatidylinositol 3-monophosphate.,tissue specificity:Ubiquitous., |
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