Price range: $268.00 through $328.00
Background:
This gene encodes a transmembrane protein that is necesssary for mechanotransduction in cochlear hair cells of the inner ear. Mutations in this gene may underlie hereditary disorders of balance and hearing. [provided by RefSeq, Aug 2015],
| Size | 50μL/100μL |
| Target | TMC2 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 100kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human TMC2 AA range: 705-755 |
| Specificity | This antibody detects endogenous levels of TMC2 at Human/Mouse |
| Gene Name | TMC2 C20orf145 UNQ907/PRO1928 |
| Protein Name | TMC2 |
| Other Name | |
| Species | Human |
| Gene ID | 117532 |
| Uniprot | Q8TDI7, |
| Species.1 | Mouse |
| Gene ID.1 | 192140 |
| Uniprot.1 | Q8R4P4 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cell membrane; Multi-pass membrane protein . Localized to the stereocilia of the cochlear hair cells. . |
| Tissue Expression | Detected in fetal cochlea. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:May be required for the normal function of cochlear hair cells.,similarity:Belongs to the TMC family.,tissue specificity:Detected in fetal cochlea., |
