Price range: $268.00 through $328.00
Background:
This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. The expression of this gene was shown to be induced by retinoic acid in a cell line expressing a oncogenic version of the retinoic acid receptor alpha fusion protein, which suggested that this gene may be a retinoic acid target gene in acute promyelocytic leukemia. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | TNFα-IP 2 |
| Reactivity | Human, Mouse |
| Applications | IHC, IF, ELISA |
| MW(Calculated) | 73kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TNAP2. AA range:131-180 |
| Specificity | TNFα-IP 2 Polyclonal Antibody detects endogenous levels of TNFα-IP 2 protein. |
| Gene Name | TNFAIP2 |
| Protein Name | Tumor necrosis factor alpha-induced protein 2 |
| Other Name | TNFAIP2; / Tumor necrosis factor alpha-induced protein 2; / TNF alpha-induced protein 2; / Primary response gene B94 protein |
| Species | Human |
| Gene ID | 7127 |
| Uniprot | Q03169, |
| Species.1 | Mouse |
| Gene ID.1 | 21928 |
| Uniprot.1 | Q61333 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | exocyst,extracellular space, |
| Tissue Expression | Umbilical vein endothelial cell, |
| Signaling_pathway | |
| Research Areas | |
| Function | developmental stage:Differentially expressed in development and capillary tube-like formation in vitro.,Function:May play a role as a mediator of inflammation and angiogenesis.,induction:By TNF-alpha and other proinflammatory factors.,similarity:Belongs to the SEC6 family., |
