Name: TNRC4 rabbit pAb
SKU: WP8694
Price: 268 USD
Availability: InStock

TNRC4 rabbit pAb

Ucallm_WP8694-50

Price range: $268.00 through $328.00

Size

100μl

50μl

Clear

SKU: WP8694-100

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Product details

Background:

Specifications

Size	50μL/100μL
Target	CELF3
Reactivity	Human, Mouse
Applications	WB
MW(Calculated)	51kD
MW(Observed)
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-2000
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	Synthesized peptide derived from human TNRC4
Specificity	This antibody detects endogenous levels of TNRC4 at Human, Mouse
Gene Name	CELF3 BRUNOL1 CAGH4 ERDA4 TNRC4
Protein Name	CUGBP Elav-like family member 3 (CELF-3) (Bruno-like protein 1) (CAG repeat protein 4) (CUG-BP- and ETR-3-like factor 3) (ELAV-type RNA-binding protein 1) (ETR-1) (Expanded repeat domain protein CAG/CTG 4) (RNA-binding protein BRUNOL-1) (Trinucleotide repeat-containing gene 4 protein)
Other Name
Species	Human
Gene ID	11189
Uniprot	Q5SZQ8,
Species.1	Mouse
Gene ID.1	78784
Uniprot.1	Q8CIN6
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	Nucleus . Cytoplasm .
Tissue Expression	Expressed in brain.
Signaling_pathway
Research Areas
Function	RNA-binding protein involved in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Activates the splicing of MAPT/Tau exon 10. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA.