SKU: WP14819 Categories: ,

Tom20 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP14819-100
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Product details

Background:

function:Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with tom22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the tom40 translocation pore., similarity:Belongs to the Tom20 family., subunit:Forms part of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex) which consists of at least 7 different proteins (TOMM5, TOMM6, TOMM7, TOMM20, TOMM22, TOMM40 and TOMM70). Interacts with TOM22.,

Specifications

Size50μL/100μL
TargetTOMM20
ReactivityHuman, Mouse, Rat
ApplicationsWB, IF, ELISA
MW(Calculated)
MW(Observed)17kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; IF 1:100-300; ELISA 1:5000-20000; Not yet tested in other applications.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human TOMM20. AA range:15-64
SpecificityTom20 Polyclonal Antibody detects endogenous levels of Tom20 protein.
Gene NameTOMM20
Protein NameMitochondrial import receptor subunit TOM20 homolog
Other NameTOMM20; / KIAA0016; / Mitochondrial import receptor subunit TOM20 homolog; / Mitochondrial 20 kDa outer membrane protein; / Outer mitochondrial membrane receptor Tom20
SpeciesHuman
Gene ID9804
UniprotQ15388,
Species.1Mouse
Gene ID.167952
Uniprot.1Q9DCC8,
Species.2Rat
Gene ID.2266601
Uniprot.2Q62760
Cellular LocalizationMitochondrion outer membrane; Single-pass membrane protein .
Tissue ExpressionBone marrow,Brain,Cervix,Epithelium,Eye,Fibroblast,Pancreas
Signaling_pathwayCellular Processes >> Transport and catabolism >> Mitophagy - animal
Research Areas
FunctionFunction:Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with tom22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the tom40 translocation pore.,similarity:Belongs to the Tom20 family.,subunit:Forms part of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex) which consists of at least 7 different proteins (TOMM5, TOMM6, TOMM7, TOMM20, TOMM22, TOMM40 and TOMM70). Interacts with TOM22.,
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